Sophia Schedin Weiss,
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Affiliation(s):
Karolinska Institutet; Department of Neurobiology; Care Sciences and Society; Division of Neurogeriatrics
Areas of Interest:
APP processing, Abeta, confocal microscopy, super-resolution microscopy, protein biochemistry, glycomics, protein glycosylation
Biography & Research:
I have a PhD in biochemistry from Stockholm University. I did a postdoc at the Swedish University for Agricultural Sciences, Uppsala, specializing in protein-protein and protein-glycan interactions. I obtained my docentur (Associate Professor) in medical biochemistry at Uppsala University in 2008. Since 2010 I am enrolled in research related to Alzheimer disease at Karolinska Institutet. My main focus areas are to study the subcellular location of APP processing, including Abeta formation, in neurons using confocal microscopy and super-resolution microscopy, as well as to identify glycan biomarkers for Alzheimer disease and other neurodegenerative disorders. I have a broad knowledge in medical biochemistry and cell biology. Areas of expertise include Fluorescence labelling, Confocal microscopy, Super-resolution microscopy including STED and STORM, Protein-protein and protein-glycan Interactions, Kinetics and equilibrium binding interaction theory, Proximity ligation assay (PLA), Glycobiology, Mice work, Culturing of primary neurons, Transfection, Transduction, Neurobiology, Alzheimer disease, Immunohistochemistry, Immunocytochemistry, Method development, Chromatography. Furthermore, I have experience from Proteomics, Mass Spectrometry, Western blotting.
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