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Patricia Jumbo-Lucioni, MD, PhD
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Affiliation(s):
Samford University; University of Alabama at Birmingham
Areas of Interest:
aging, Alzheimer's disease genetics, energy metabolism, Skeletal Muscle
Biography & Research:
After completion of her medical training in Lima, Peru, Patricia Jumbo-Lucioni pursued her Ph.D. in Nutrition sciences at the University of Alabama at Birmingham (UAB) in 2004. As a graduate student at UAB, Jumbo-Lucioni gained research experience in the genetics of complex traits and mitochondria physiology using Drosophila melanogaster, the fruit fly, as experimental organism. Upon graduation in 2009, she continued her postdoctoral training at the department of human genetics at Emory University and later joined the department of biological sciences at Vanderbilt University.
As post-doctoral fellow, Jumbo-Lucioni gained further expertise in fly genetics and genetics of carbohydrate metabolism, and the role of glycosylation defects in the development and function of neuromuscular synapses. She joined Samford University as an assistant professor in January 2016 and decided to pursue her interest on neurological disorders. Her laboratory focuses on elucidating the role of the renin angiotensin system on the pathophysiology of Alzheimer’s disease using a well-established Drosophila model. Her lab is working on characterizing behavioral traits and molecular markers of disease after pharmacological blockade of the renin angiotensin system in this model.
Additionally, through collaboration with researchers at UAB, Jumbo-Lucioni's laboratory is exploring the role of the gut microbiome as a therapeutical target to ameliorate cognitive deficits in our fly model of Alzheimer’s disease.