Siddhartha Mondragon Rodriguez, BSc (Hons) MSc PhD
Primary tabs
JAD profile
Associate Editor
Term Expiration:
12/31/2024
Affiliation(s):
UNAM
Lab URL:
Areas of Interest:
Alzheimer's disease Tauopathies Biomarkers
Biography & Research:
Dr. Siddhartha Mondragón-Rodríguez graduated in Chemical Engineering from Michoacán University of Saint Nicolas of Hidalgo (UMSNH) in 1996 - 2002. Master’s Degree (MsC) in Molecular Biomedicine from National School of Medicine from the National Polytechnic Institute of Mexico City in 2003 - 2005. PhD from Center of Research and Advanced Studies of the National Politechnical Institute in 2005 – 2009. During this time, he analyzed the relationship between the amyloid beta protein (Ab) and the neurofibrillary tangles built from phosphorylated tau protein in human Alzheimer´s brains, the most important proteins known to be related to Alzheimer´s disease (AD). Research Invited at Case Western Reserve University, Department of Pathology, Cleveland, Ohio, US, in 2006 - 2007. Where he aimed to compare his AD findings to other tau related neurological diseases such as Pick disease, Fronto-temporal dementia, Progressive Supranuclear Palsy and Parkinson’s disease. He was a H.H. Jasper postdoctoral Fellow from Universite de Montreal in 2009 - 2012. Faculte de Medecine, Departament de Physiologie., Montreal, Qc, Canada. At that time, he aimed to unveil the relationship between phosphorylated tau protein and one of the most fundamental events in the brain, synaptic plasticity and its long-lasting forms (LTD and LTP) who have been proposed to be affected by Ab during AD. Then, he obtained the Fonds du recherche du santé du Quebec postdoctoral fellowship at McGill University, Faculte de Medicine, Department of Psychiatry, Montreal, QC, Canada from 2012 to 2014. That allowed him to study the brain network alterations during neurodegeneration. Since 2014, he moved to the Department of Developmental Neurobiology and Neurophysiology, where he is currently studying the role of tau phosphorylation in brain network communication.
