Mohammad Sabbir, BSc (Hons) PhD
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JAD profile
Associate Editor
Term Expiration:
12/31/2024
Affiliation(s):
Nova Southeastern University
ORCID URL:
Areas of Interest:
Alzheimer's disease
Biography & Research:
Dr. Sabbir is an Instructor in the Department of Pharmaceutical Sciences, Health Professions Division, College of Pharmacy, NSU. Dr. Sabbir received Ph.D. in Head and Neck Cancer molecular biology and has extensive postdoctoral research experience in a wide variety of health-related disciplines, including Neurodegenerative disorders, specifically Diabetes-induced peripheral neuropathy, and Alzheimer’s disease. Dr. Sabbir’s research focuses on the fundamental and discovery science relating to Alzheimer’s disease and Atherosclerosis, and the advancement and commercialization of novel diagnostic approaches and therapeutic targets for these diseases. On the Alzheimer's front, Dr. Sabbir is focused on his discovery of a calcium-activated kinase (CAMKK2) signaling-mediated trafficking of an iron transporter protein, transferrin. Dr. Sabbir's research revealed abnormal CAMKK2-Transferrin trafficking underlies iron dyshomeostasis-mediated neurodegeneration in Alzheimer's. On the Atherosclerosis front, Dr. Sabbir is studying the role of CAMKK2 in trans-endothelial transferrin trafficking and iron overloading in atherosclerotic lesions and its implications in the pathogenesis of the disease. Furthermore, Dr. Sabbir is also engaged in developing a novel diagnostics approach for the detection of early signs of cardiovascular diseases, specifically Atherosclerosis, and identified new signaling pathways and druggable targets for the prevention of chronic inflammation. Another line of Dr. Sabbir’s research is based on the discovery of novel antisense long non-coding RNA (lncRNA)-mediated regulation of arachidonic lipoxygenase gene which regulates inflammation and is linked to chronic inflammatory disease including Atherosclerosis.
