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Romeu Videira, PhD
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Affiliation(s):
University of Trás-os-Montes e Alto Douro (UTAD)
ORCID URL:
Areas of Interest:
acetylcholinesterase inhibitors, aging, Alzheimer’s disease, amyloid, functional lipidomics, membrane organization, mitochondria, neuroinflammation, oxidative stress
Biography & Research:
Romeu Videira (RV - male) was graduated in Biochemistry, University of Coimbra, in 1993, and achieved his Ph.D. degree in 2003, in Biochemistry - Biochemical Toxicology, University of Coimbra. Romeu Videira worked as a teaching assistant (1998-2009) in Escola Superior de Tecnologia de Viseu (EST-IPV). Currently, Romeu Videira is senior researcher in CQ-VR, University of Tras-os-Montes e Alto Douro (UTAD).
The main objectives of his scientific activity are: i) to understand the molecular mechanisms and biochemical pathways used by organisms to regulate dynamically, throughout all life, the lipid composition of the membranes of its cells; with particular focus on the homeostatic interconnectivity among the profile of mitochondrial cardiolipins, the bioenergetic metabolism and the cellular redox state. He is investigating how the breakdown of these specific homeostatic process is related with the inception and progression of Alzheimer’s disease, in order to identify novel molecular biomarkers and targets for therapeutic intervention. ii) to develop nanomedical platforms, combining graphene-based nanotechnological tools (redox-labile carbon nanomaterials) with unilamellar lipossomes prepared with specific set of phospholipids to overcome the mitochondrial dysfunctions associated with age-related human pathologies, including Alzheimer’s disease.
Romeu Videira was the principal investigator of 3 projects funded by national funding agencies and throughout the years he has been team member of 4 other funded projects. He is author of 4 book chapters, 28 research articles and 6 proceedings in international peer-reviewed scientific journals, 500 citations and h factor (Scopus): 12.