Martin Vyhnalek, Associate Professor

JAD profile

Associate Editor

Term Expiration: 

12/31/2026

Affiliation(s): 

Charles University Prague; Motol University Hospital; St. Anne’s University Hospital Brno

Areas of Interest: 

aging, Alzheimer's disease, cerebrospinal fluid, executive functions, memory, mild cognitive impairment, neuropsychology, olfaction, subjective cognitive decline

Biography & Research: 

Associate professor Martin VYHNÁLEK, M. D., Ph.D. Mailing Address: Phone Number: E-mail: Neurology Clinic, 2nd Medical Faculty, Charles University, V Úvalu 84, 150 06 Praha 5 +420-736 409 881 Martin.vyhnalek@fnmotol.cz Education: Postgraduate: - Associate professor in Neurology – Charles University – (2020) - PhD degree in Neurosciences (2015) - Specialization in Neurology 2nd degree – 2008, Prague - University Diploma in Movement Disorders (DEU), Medical School, Pierre et Marie Curie University, Paris, France (2005-2006) - Specialization in Neurology (1st degree) – 2005, Prague - University Diploma in Clinical Neuropsychology (DEU), Medical School, University Montpellier, France (2001-2002) - University Diploma in Diagnosis and Treatment of Alzheimer Disease and Associated Disorders (DEU), Medical School, University Montpellier I, France (2001-2002) - Certificate of Specialization in Neurology, Medical School, University Montpellier I, France (2001-2003) Undergraduate: - 2nd Medical School, Charles University Prague (1995-2001) - Gymnázium Jana Nerudy, Prague, Czech republic 1990-1995 (bilingual high school, education in French language) Employment: - Department of Neurology, 2nd Medical School, Charles University ( 2003– now), actually – Associate professor, Head of the Center of hereditary ataxias, head of Neuropsychological laboratory, head of outpatient clinic. - Resident at Cognitive and Behavioral Neurological Clinic, University Montpellier I, France (2001-2003) Clinical Fellowship and courses: - Course in Biomedical Statistics (EuroMise – Czech Academy of Sciences) - Department of Neurology, Emille Muller Hospital, Mullhouse, France 1 month – French government scholarship (2001) - Research fellowship Neurologie Pitié-Salpetriere, INSERM U 679 Paříž – Neurologie et Therapeutique experimentale (French government scholarship), duration 3 months. 09-12/2005 - Dpt. Of Neurology – Montpellier University Hospital - clinical fellowship, neurodegenerative diseases (4 months) 02-05/ 2009 - Mayo Clinic, Scottsdale, Arizona, USA 11/2011 - Mayo Clinic, Rochester, Minnesota, USA 7/2012 - Cognitive Aging and Neurophysiology of Aging Labs, School of Aging Studies, University of South Florida, Tampa, Florida, USA 02/2014 – 05/2014 - Other experience: - Associate Editor in Journal of Alzheimer's Disease (2017 – 2019) - Reviewer (journals) - Journal of Geriatric Psychiatry and Neurology, Current Alzheimer research, European Journal of Neuroscience, American Journal of Alzheimers Disease & Other Dementias, Česká a slovenská neurologie a neurochirurgie, Neurologie pro praxi, Psychiatrie pro praxi, - Reviewer (grants – grant agencies): IGA, AZV, GAČR, SRDA (Slovak research development agency), GAUK - Rater and co investigator of Clinical Trials (1 international multicentre trial on vascular dementia and 8 multicentre trials on Alzheimer disease) - National language expert for Eli Lilly H6L-MC-LFAN Investigator’s Meeting training Czech raters for ADAS-Cog, ADCS-ADL, CDR and CIBIC tests and scales, - Consultant for Bracket in 5 AD trials (2014-2020) - Author of Neuropsychological battery and neuropsychiatric scales used in Czech longitudinal study on cognitive impairment. Creator and author of study database - Grant projects - Principle investigator of 2 grant projects: 1) Qualitative and quantitative analysis of olfactory impairment in the early stages of Alzheimer's disease and cognitive impairment of other etiologies GAUK 91007 (2007 – 2009) - rating: exceptionally good 2) The Validation of specific mitophagy biomarkers across Alzheimer’s disease continuum – EAA Grants and the Technology Agency of the Czech Republic within the KAPPA Programme (2021-2024 – ongoing) - Coinvestigator of 2 grants projects 1) Diagnosis of Alzheimer's disease based on the detection of amyloid beta peptide complexes with certain endogenous substances in cerebrospinal fluid - IGA NT 11225 – 4 (2010 – 2013) co-investigator in Motol University Hospital, principal investigator: Ing. Zdena Krištofiková, Ph.D., rating – excellent 2) Interaction of intracellular amyloid beta and the diagnosis of Alzheimer's disease AZV - 16-27611A (2016 – 2019)‒ co-investigator in Motol University Hospital, principal investigator: Ing. Zdena Krištofiková, Ph.D., rating – excellent - Member of the research team in 15 other grant projects. Membership: - Czech Neurological Society - Section for Cognitive Neurology of the Czech Neurological Society – member of the Management Board - EU Joint Programme - Neurodegenerative Disease Research (JPND)– member of the management board (2010-2014) - ERN-RND (European reference network, rare neurological diseases) – member of the panel Languages: - Czech - native language - English – fluent - French - fluent Publications – summary : Number of publications – 180 (WOS), H-index 23 (WOS, 10-DEC-2022), times cited (WOS) 1791, 1 monography, 8 book chapters. Prague 12-DEC-2022 Martin Vyhnálek